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Twist2tm1(cre/ERT2)Eno
Targeted Allele Detail
Summary
Symbol: Twist2tm1(cre/ERT2)Eno
Name: twist basic helix-loop-helix transcription factor 2; targeted mutation 1, Eric N Olson
MGI ID: MGI:7437699
Synonyms: Tw2-CreERT2, Tw2-CreERT2-neo
Gene: Twist2  Location: Chr1:91729183-91775750 bp, + strand  Genetic Position: Chr1, 46.24 cM
Alliance: Twist2tm1(cre/ERT2)Eno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:246973
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Twist2tm1(cre/ERT2)Eno expression driven by 1 gene
    A CreERT2-Frt-Neo-Frt expression cassette was inserted to replace exon 1 of the Twist2 gene. (J:246973)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Twist2 (mouse)
Summary of all recombinase alleles driven by Twist2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Twist2 Mutation:  10 strains or lines available
References
Original:  J:246973 Liu N, et al., A Twist2-dependent progenitor cell contributes to adult skeletal muscle. Nat Cell Biol. 2017 Mar;19(3):202-213
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory