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Gene Expression Data
Assay Details
Assay
Reference: J:203635 Miraoui H, et al., Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet. 2013 May 2;92(5):725-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437923
Gene symbol: Il17rd
Gene name: interleukin 17 receptor D
Antibody: Anti-Il17rd
Results
Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: olfactory placode Present Regionally restricted 3D Expression was highest in the epithelium of the olfactory placode. Labeling was much milder in the mesenchyme. Label localized to the perinuclear compartment of the cell.
Specimen 3E WT: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forebrain Present Regionally restricted 3E WT Expression was detected in ventral forebrain. High expression was detected in the septal area.
Specimen 3E Hypomorph: embryonic day 12.5; Fgf8tm1.4Mrt/Fgf8tm1.4Mrt (more )
Structure Level Pattern Image Note
TS20: forebrain Absent 3E Fgf8 Hypomorph
Specimen 3E upper inset: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 3E upper inset
Specimen 3E lower inset: embryonic day 12.5 (more )
Note: Double labeled: red - Il17rd; green - Gnrh1 (assay MGI:7437924).
Structure Level Pattern Image Note
TS20: olfactory epithelium Absent 3E lower inset
Specimen S2E B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nasal pit Weak S2B Expression was dramatically decreased overall relative to E10.5.
Specimen S2E E: embryonic day 11.5 (more )
Note: Double labeled: red - Il17rd; green - Gnrh1 (assay MGI:7437924).
Structure Cell Type Level Pattern Image Note
TS19: nasal pit neuron Weak Regionally restricted S2E , S2F Expression was detected in a few Gnrh1-labeled neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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