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Crhr1tm1.1(cre/GFP)Lsz
Targeted Allele Detail
Summary
Symbol: Crhr1tm1.1(cre/GFP)Lsz
Name: corticotropin releasing hormone receptor 1; targeted mutation 1.1, Larry S Zweifel
MGI ID: MGI:7438225
Synonyms: Crhr1IRES-Cre
Gene: Crhr1  Location: Chr11:104023681-104066349 bp, + strand  Genetic Position: Chr11, 67.77 cM
Alliance: Crhr1tm1.1(cre/GFP)Lsz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:253267
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Crhr1tm1.1(cre/GFP)Lsz expression driven by 1 gene
 
Mutation details: An IRES-CreGFP sequence and frt-flanked neomycin gene were inserted into the 3 UTR of the endogenous Crhr1 gene. The neomycin resistance cassette was removed by crossing F1 offspring to FlpEr mice. (J:253267)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Crhr1 (mouse)
Summary of all recombinase alleles driven by Crhr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crhr1 Mutation:  28 strains or lines available
References
Original:  J:253267 Sanford CA, et al., A Central Amygdala CRF Circuit Facilitates Learning about Weak Threats. Neuron. 2017 Jan 4;93(1):164-178
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory