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Klhl24em1(cre/ERT2)Yyang
Endonuclease-mediated Allele Detail
Summary
Symbol: Klhl24em1(cre/ERT2)Yyang
Name: kelch-like 24; endonuclease-mediated mutation 1, Yong Yang
MGI ID: MGI:7439046
Synonyms: Klhl24-CreERT2
Gene: Klhl24  Location: Chr16:19916292-19947971 bp, + strand  Genetic Position: Chr16, 12.36 cM, cytoband B1
Alliance: Klhl24em1(cre/ERT2)Yyang page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Epitope tag, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Klhl24em1(cre/ERT2)Yyang expression driven by 1 gene
    The 3xFlag-2A-CreERT2 sequence was knocked in the stop codon site of Klhl24 by CRISPR/Cas9. (J:333463)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Klhl24 (mouse)
Summary of all recombinase alleles driven by Klhl24.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klhl24 Mutation:  35 strains or lines available
References
Original:  J:333463 Cui J, et al., KLHL24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia. J Invest Dermatol. 2022 Aug;142(8):2079-2087.e8
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory