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Tg(Tph1-EGFP/cre/ERT2)#Jmer
Transgene Detail
Summary
Symbol: Tg(Tph1-EGFP/cre/ERT2)#Jmer
Name: transgene insertion, Juanita L Merchant
MGI ID: MGI:7439062
Synonyms: Tph1-CreERT2
Transgene: Tg(Tph1-EGFP/cre/ERT2)#Jmer  Location: unknown  
Alliance: Tg(Tph1-EGFP/cre/ERT2)#Jmer page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Tph1-EGFP/cre/ERT2)#Jmer expression driven by 1 gene
 
Mutation details: A 3,718-bp cassette containing the fusion of sequence-encoding enhanced green fluorescent protein (eGFP), Cre recombinase, and the mutant estrogen ligand-binding domain (ERT2) was inserted into a BAC clone (RP23-29A7) containing the full-length gene encoding Tph1 at the ATG start codon. The eGFP protein fluorescence expression is not detectable. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:333475)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tph1 (mouse)
Summary of all recombinase alleles driven by Tph1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:333475 Sei Y, et al., Mature enteroendocrine cells contribute to basal and pathological stem cell dynamics in the small intestine. Am J Physiol Gastrointest Liver Physiol. 2018 Oct 1;315(4):G495-G510
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory