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Nppatm3.1(cre/ERT2)Bzsh
Targeted Allele Detail
Summary
Symbol: Nppatm3.1(cre/ERT2)Bzsh
Name: natriuretic peptide type A; targeted mutation 3.1, Bin Zhou
MGI ID: MGI:7439151
Synonyms: Nppa-CreER
Gene: Nppa  Location: Chr4:148085179-148086531 bp, + strand  Genetic Position: Chr4, 78.66 cM
Alliance: Nppatm3.1(cre/ERT2)Bzsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263128
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Nppatm3.1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: A cDNA encoding Cre/ERT2 was inserted into the translational stop codon of Nppa gene (before 3 UTR), with a self-cleaving 2 A peptide sequence linking Nppa and cre/ERT2. (J:263128)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nppa (mouse)
Summary of all recombinase alleles driven by Nppa.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nppa Mutation:  11 strains or lines available
References
Original:  J:263128 Tian X, et al., Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun. 2017 Jul 20;8(1):87
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory