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Sema3atm1.1(cre/ERT2)Bzsh
Targeted Allele Detail
Summary
Symbol: Sema3atm1.1(cre/ERT2)Bzsh
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1.1, Bin Zhou
MGI ID: MGI:7439154
Synonyms: Sema3a-CreER
Gene: Sema3a  Location: Chr5:13175381-13652533 bp, + strand  Genetic Position: Chr5, 4.31 cM
Alliance: Sema3atm1.1(cre/ERT2)Bzsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263128
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Sema3atm1.1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: A cDNA encoding Cre recombinase fused with a mutant form of the estrogen receptor hormone-binding domain (CreERT2) was inserted in frame with the translational start codon of the Sema3a gene. (J:263128)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sema3a (mouse)
Summary of all recombinase alleles driven by Sema3a.
 

Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3a Mutation:  48 strains or lines available
References
Original:  J:263128 Tian X, et al., Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun. 2017 Jul 20;8(1):87
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory