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Pdgfctm2.1(cre/ERT2)Hdin
Targeted Allele Detail
Summary
Symbol: Pdgfctm2.1(cre/ERT2)Hdin
Name: platelet-derived growth factor, C polypeptide; targeted mutation 2.1, Hao Ding
MGI ID: MGI:7439353
Synonyms: Pdgf-cCreERT2
Gene: Pdgfc  Location: Chr3:80943723-81121347 bp, + strand  Genetic Position: Chr3, 35.73 cM
Alliance: Pdgfctm2.1(cre/ERT2)Hdin page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:257668
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pdgfctm2.1(cre/ERT2)Hdin expression driven by 1 gene
 
Mutation details: A FRT flanked SA-IRESbgeo cassette, and T2A-CreERT2 are inserted into exon 6 before the stop codon of the Pdgfc gene. The FRT flanked SA-IRESbgeo cassette was removed by Flpe-mediated recombination. (J:257668)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfc (mouse)
Summary of all recombinase alleles driven by Pdgfc.
 

Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfc Mutation:  35 strains or lines available
References
Original:  J:257668 Wu X, et al., A Pdgf-c(CreERT2) knock-in mouse model for tracing PDGF-C cell lineages during development. Genesis. 2018 Feb;56(2)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory