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Pdgfrbem1(icre)Bcgen
Endonuclease-mediated Allele Detail
Summary
Symbol: Pdgfrbem1(icre)Bcgen
Name: platelet derived growth factor receptor, beta polypeptide; endonuclease-mediated mutation 1, Biocytogen LLC
MGI ID: MGI:7439912
Synonyms: B-Pdgfrb-iCre, Pdgfrb-Cre, Pdgfrbtm1(iCre)
Gene: Pdgfrb  Location: Chr18:61178222-61218133 bp, + strand  Genetic Position: Chr18, 34.41 cM
Alliance: Pdgfrbem1(icre)Bcgen page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Pdgfrbem1(icre)Bcgen expression driven by 1 gene
 
Mutation details: An F2A-iCre sequence cassette was placed between the coding sequence of exon 23 and 3UTR of the Pdgfrb gene using CRISPR/Cas9 technology. (J:333644)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfrb (mouse)
Summary of all recombinase alleles driven by Pdgfrb.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfrb Mutation:  87 strains or lines available
References
Original:  J:333644 Suo L, et al., METTL3-mediated N (6)-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication. Theranostics. 2022;12(1):277-289
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory