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Cbln4tm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Cbln4tm1.1(cre/GFP)Rpa
Name: cerebellin 4 precursor protein; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:7439917
Gene: Cbln4  Location: Chr2:171878256-171885386 bp, - strand  Genetic Position: Chr2, 94.74 cM
Alliance: Cbln4tm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:331457
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Cbln4tm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Cb;m4 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:331457)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cbln4 (mouse)
Summary of all recombinase alleles driven by Cbln4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cbln4 Mutation:  19 strains or lines available
References
Original:  J:331457 Pauli JL, et al., Molecular and anatomical characterization of parabrachial neurons and their axonal projections. Elife. 2022 Nov 1;11
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory