About   Help   FAQ
Tacr1tm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Tacr1tm1.1(cre/GFP)Rpa
Name: tachykinin receptor 1; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:7439920
Gene: Tacr1  Location: Chr6:82379315-82537085 bp, + strand  Genetic Position: Chr6, 35.94 cM, cytoband D1
Alliance: Tacr1tm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:331457
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Tacr1tm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Tarc1 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:331457)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tacr1 (mouse)
Summary of all recombinase alleles driven by Tacr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tacr1 Mutation:  40 strains or lines available
References
Original:  J:331457 Pauli JL, et al., Molecular and anatomical characterization of parabrachial neurons and their axonal projections. Elife. 2022 Nov 1;11
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory