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Htr2cem1(icre)Ylu
Endonuclease-mediated Allele Detail
Summary
Symbol: Htr2cem1(icre)Ylu
Name: 5-hydroxytryptamine (serotonin) receptor 2C; endonuclease-mediated mutation 1, Youming Lu
MGI ID: MGI:7442224
Synonyms: Htr2c-Cre
Gene: Htr2c  Location: ChrX:145745509-145980273 bp, + strand  Genetic Position: ChrX, 68.46 cM, cytoband D-F4
Alliance: Htr2cem1(icre)Ylu page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Htr2cem1(icre)Ylu expression driven by 1 gene
    Using CRISPR/Cas9 system, P2A-iCRE was inserted between the Htr2c Exon 6 and 3-UTR regions. (J:267056)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Htr2c (mouse)
Summary of all recombinase alleles driven by Htr2c.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htr2c Mutation:  13 strains or lines available
References
Original:  J:267056 Li X, et al., Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus. Nat Neurosci. 2018 Sep;21(9):1239-1250
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory