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Tg(Gata3-cre)2471Jeng
Transgene Detail
Summary
Symbol: Tg(Gata3-cre)2471Jeng
Name: transgene insertion 2471, James Douglas Engel
MGI ID: MGI:7442300
Synonyms: TgOVE-Cre
Transgene: Tg(Gata3-cre)2471Jeng  Location: unknown  
Alliance: Tg(Gata3-cre)2471Jeng page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gata3-cre)2471Jeng expression driven by 1 gene
 
Mutation details: A 1.3-kb DNA fragment bearing the (300-bp) Gata3 promoter plus 1 kb of the first intron was linked to the 1.5kb genomic sequence of the otic vesicle enhancer (OVE) corresponding to +571 in the Gata3 locus in BAC clone 260A19 drives cre expression to the inner ear specifically. Two lines 2471 and 2476 were established. (J:267996)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata3 (mouse)
Summary of all recombinase alleles driven by Gata3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:267996 Moriguchi T, et al., A Gata3 3' Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression. Mol Cell Biol. 2018 Nov 1;38(21)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory