About   Help   FAQ
Tg(Gata3*-cre)2481Jeng
Transgene Detail
Summary
Symbol: Tg(Gata3*-cre)2481Jeng
Name: transgene insertion 2481, James Douglas Engel
MGI ID: MGI:7442302
Synonyms: TgcoreOVE-Cre, TgOVE core-Cre
Transgene: Tg(Gata3*-cre)2481Jeng  Location: unknown  
Alliance: Tg(Gata3*-cre)2481Jeng page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gata3*-cre)2481Jeng expression driven by 1 gene
 
Mutation details: A 1.3-kb DNA fragment bearing the (300-bp) Gata3 promoter plus 1 kb of the first intron was linked to the 3' 246-bp sequence from the otic vesicle enhancer (OVE) referred to as the core OVE in the Gata3 locus in BAC clone 260A19 drives cre expression to the inner ear specifically. One line 2481 was established. (J:267996)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata3 (mouse)
Summary of all recombinase alleles driven by Gata3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:267996 Moriguchi T, et al., A Gata3 3' Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression. Mol Cell Biol. 2018 Nov 1;38(21)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory