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Gene Expression Data
Assay Details
Assay
Reference: J:268713 Schweiger PJ, et al., Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro. Sci Rep. 2018 Oct 15;8(1):15255
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7442842
Gene symbol: Lrig1
Gene name: leucine-rich repeats and immunoglobulin-like domains 1
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B - small intestine: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 1B Small intestine - upper Expression is seen in cells at the bottom of the crypt.
Specimen 1B - skin: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 1B Skin - upper Expression is seen within the junctional zone of the pilosebaceous unit in the epidermis.
Specimen 1F - corpus: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Double labeled: green - Lrig1 reporter; red - Lrig1 protein (assay MGI:7443063).
Structure Level Pattern Image Note
TS28: body of stomach Present Regionally restricted 1F Corpus Expression is seen in a discrete subset of cells located at the bottom of the glands.
TS28: stomach glandular region Present Regionally restricted 1F Corpus Expression is seen in a discrete subset of cells located at the bottom of the glands.
Specimen 1F - pylorus: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Double labeled: green - Lrig1 reporter; red - Lrig1 protein (assay MGI:7443063).
Structure Level Pattern Image Note
TS28: stomach glandular epithelium Present Regionally restricted 1F Pylorus Expression is seen in a discrete subset of cells located at the bottom of the glands.
TS28: stomach pyloric region Present Regionally restricted 1F Pylorus Expression is seen in a discrete subset of cells located at the bottom of the glands.
Specimen 1F - forestomach: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Double labeled: green - Lrig1 reporter; red - Lrig1 protein (assay MGI:7443063).
Structure Level Pattern Image Note
TS28: stomach proventricular region epithelium Present Widespread 1F Forestomach Ubiquitous expression is seen in the basal layer.
Specimen 2G - right: postnatal; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Double labeled: green - Lrig1; red - Chga (assay MGI:7443066).
Structure Level Pattern Image Note
TS28: body of stomach Present Regionally restricted 2G right Some expressing cells also co-express chromogranin A.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory