Cxcr5<em1(cre/ERT2)Yhar> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7443960)

Cxcr5^{em1(cre/ERT2)Yhar}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Cxcr5^{em1(cre/ERT2)Yhar}
Name:	C-X-C motif chemokine receptor 5; endonuclease-mediated mutation 1, Yohsuke Harada
MGI ID:	MGI:7443960
Synonyms:	Cxcr5^CreERT2
Gene:	Cxcr5 Location: Chr9:44423084-44437741 bp, - strand Genetic Position: Chr9, 24.84 cM
Alliance:	Cxcr5^{em1(cre/ERT2)Yhar} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Cxcr5^{em1(cre/ERT2)Yhar} expression driven by 1 gene

Using the CRISPR/Cas9 system, the P2A sequence and CreERT2 was inserted into the Cxcr5 3'UTR. (J:270146)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cxcr5 (mouse) Summary of all recombinase alleles driven by Cxcr5. Comparative matrix view of recombinase activities Alliance mouse Cxcr5 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cxcr5 Mutation:	28 strains or lines available

References

Original:	J:270146 Takebe T, et al., A novel mouse model for tracking the fate of CXCR5-expressing T cells. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1642-1647
All:	1 reference(s)

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