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Gene Expression Data
Assay Details
Assay
Reference: J:310899 Ramesova A, et al., Caspase-1 Inhibition Impacts the Formation of Chondrogenic Nodules, and the Expression of Markers Related to Osteogenic Differentiation and Lipid Metabolism. Int J Mol Sci. 2021 Sep 3;22(17)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7444318
Gene symbol: Casp1
Gene name: caspase 1
Antibody: anti-Casp1 p20 (Cleaved Asp296) (PA5-99390)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The antibody used recognizes the activated form of the protein.
Results
Specimen 1A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forelimb pre-cartilage condensation Present Regionally restricted 1A Expression is in the bcondensed mesenchyme of the future growth plate.
Specimen 1B: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: forelimb cartilage condensation chondrocyte Present Regionally restricted 1B Expression is in resting zones of the growth plate.
Specimen 1C: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: forelimb cartilage condensation chondrocyte Present Regionally restricted 1C Expression is in proliferating zones of the growth plate.
Specimen 1D: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: forelimb cartilage condensation hypertrophic chondrocyte Present Regionally restricted 1D Expression is in hypertrophic zones of the growth plate.
Specimen 1E: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: forelimb cartilage condensation osteoclast Present Regionally restricted 1E Expression is in chondroclasts and osteoclasts penetrating to the primary ossification center. Expression is absent in the zone of calcifying cartilage.
Specimen 1F: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb cartilage condensation Present Regionally restricted 1F Expression is in resting and proliferating zones of the growth plate.
Specimen 1G: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: forelimb cartilage condensation hypertrophic chondrocyte Weak Regionally restricted 1G Expression is in hypertrophic and ossification zones of the growth plate.
Specimen 1H: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: forelimb cartilage condensation osteoclast Present Regionally restricted 1H Expression is in osteoclasts of the ossification zones
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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