Cfap61<em1Cya> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7444390)

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Cfap61^em1Cya
Endonuclease-mediated Allele Detail

Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Summary

Symbol:	Cfap61^em1Cya
Name:	cilia and flagella associated protein 61; endonuclease-mediated mutation 1, Cyagen Biosciences
MGI ID:	MGI:7444390
Synonyms:	Cfap61^em1C
Gene:	Cfap61 Location: Chr2:145776704-146056959 bp, + strand Genetic Position: Chr2, 71.28 cM
Alliance:	Cfap61^em1Cya page

Mutation
origin

Strain of Origin:

C57BL/6N

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		CRISPR/Cas9 technology generated a 4227 bp deletion encompassing exons 3 to 5. (J:333907)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cfap61 Mutation:	63 strains or lines available

References

Original:	J:333907 Huang T, et al., Absence of murine CFAP61 causes male infertility due to multiple morphological abnormalities of the flagella. Sci Bull (Beijing). 2020 May 30;65(10):854-864
All:	1 reference(s)

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