About   Help   FAQ
Tg(CAG-flpe)32Ito
Transgene Detail
Summary
Symbol: Tg(CAG-flpe)32Ito
Name: transgene insertion 32, Shigeyoshi Itohara
MGI ID: MGI:7444772
Synonyms: CAG-FLPe
Transgene: Tg(CAG-flpe)32Ito  Location: unknown  
Alliance: Tg(CAG-flpe)32Ito page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(CAG-flpe)32Ito expression driven by 1 gene
 
Mutation detailsThe CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a FLPe gene with a nuclear localization signal. Five founder lines were established (lines 16, 32, 36, 37 and 41) with lines 16, 32 and 36 exhibiting 100% recombination when crossed to a mouse containing an frt-flanked allele; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. (J:108559)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory