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Emx1tm1.1(flpo)Jmac
Targeted Allele Detail
Summary
Symbol: Emx1tm1.1(flpo)Jmac
Name: empty spiracles homeobox 1; targeted mutation 1.1, Jeffrey D Macklis
MGI ID: MGI:7444792
Synonyms: Emx1-IRES-FlpO
Gene: Emx1  Location: Chr6:85164913-85181445 bp, + strand  Genetic Position: Chr6, 37.21 cM
Alliance: Emx1tm1.1(flpo)Jmac page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Emx1tm1.1(flpo)Jmac expression driven by 1 gene
 
Mutation details: By standard gene targeting procedures, an IRES-FlpO cassette was introduced into the 3' untranslated region of the Emx1 gene followed by a loxP-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette. (J:328745)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Emx1 (mouse)
Summary of all recombinase alleles driven by Emx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Emx1 Mutation:  34 strains or lines available
References
Original:  J:328745 Sahni V, et al., Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Cell Rep. 2021 Oct 19;37(3):109843
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory