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Cdh5em1(nigri)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Cdh5em1(nigri)Bzsh
Name: cadherin 5; endonuclease-mediated mutation 1, Bin Zhou
MGI ID: MGI:7444934
Synonyms: Cdh5-Nigri
Gene: Cdh5  Location: Chr8:104828257-104871143 bp, + strand  Genetic Position: Chr8, 53.04 cM
Alliance: Cdh5em1(nigri)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout, Recombinase)
Mutation:    Insertion
 
Cdh5em1(nigri)Bzsh expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 methods, a cDNA encoding the Nigri (recombinase identified and isolated from bacteria sp Vibrio nigripulchritudo) cassette was inserted into the second exon of the Cdh5 gene. (J:266564)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh5 (mouse)
Summary of all recombinase alleles driven by Cdh5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh5 Mutation:  59 strains or lines available
References
Original:  J:266564 Liu K, et al., A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development. 2018 Sep 17;145(18):dev167775
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory