Mrc1<em1(cre/ERT2)Mp> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7446934)

Mrc1^{em1(cre/ERT2)Mp}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Mrc1^{em1(cre/ERT2)Mp}
Name:	mannose receptor, C type 1; endonuclease-mediated mutation 1, Marco Prinz
MGI ID:	MGI:7446934
Synonyms:	Mrc1^CreERT2
Gene:	Mrc1 Location: Chr2:14234225-14336834 bp, + strand Genetic Position: Chr2, 10.46 cM
Alliance:	Mrc1^{em1(cre/ERT2)Mp} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Mrc1^{em1(cre/ERT2)Mp} expression driven by 1 gene

The CRISPRCas9 system was used to knock-in the T2A-CreERT2 cassette into the Mrc1 locus. (J:330324)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mrc1 (mouse) Summary of all recombinase alleles driven by Mrc1. Comparative matrix view of recombinase activities Alliance mouse Mrc1 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Mrc1 Mutation:	86 strains or lines available

References

Original:	J:330324 Masuda T, et al., Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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