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Aif1tm1.1(cre)Mrc
Targeted Allele Detail
Summary
Symbol: Aif1tm1.1(cre)Mrc
Name: allograft inflammatory factor 1; targeted mutation 1.1, Mario R Capecchi
MGI ID: MGI:7446945
Synonyms: Aif1(Iba1)-IRES-Cre
Gene: Aif1  Location: Chr17:35389967-35394977 bp, - strand  Genetic Position: Chr17, 18.59 cM
Alliance: Aif1tm1.1(cre)Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:312088
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Aif1tm1.1(cre)Mrc expression driven by 1 gene
 
Mutation details: An IRES-Cre-FRT-neo-FRT cassette was inserted into the 3 untranslated region of the Aif1 gene. The neo-selection cassette was removed. (J:312088)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aif1 (mouse)
Summary of all recombinase alleles driven by Aif1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aif1 Mutation:  37 strains or lines available
References
Original:  J:312088 Pozner A, et al., Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse. Front Mol Neurosci. 2015;8:12
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory