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Il17atm1.1(EYFP/cre)Ehs
Targeted Allele Detail
Summary
Symbol: Il17atm1.1(EYFP/cre)Ehs
Name: interleukin 17A; targeted mutation 1.1, National Institute of Environmental Health Science
MGI ID: MGI:7446997
Synonyms: IL-17A-Cre, Il17a(cre/YFP)
Gene: Il17a  Location: Chr1:20801129-20804720 bp, + strand  Genetic Position: Chr1, 6.45 cM, cytoband A
Alliance: Il17atm1.1(EYFP/cre)Ehs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:307726
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Il17atm1.1(EYFP/cre)Ehs expression driven by 1 gene
 
Mutation details: generated by targeted insertion of an internal ribosome entry site (IRES) and DNA encoding a Cre recombinase/YFP fusion protein into the 39 untranslated region of the IL-17A gene. (J:307726)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il17a (mouse)
Summary of all recombinase alleles driven by Il17a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il17a Mutation:  25 strains or lines available
References
Original:  J:307726 Shalaby KH, et al., Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling. J Allergy Clin Immunol. 2018 Oct;142(4):1229-1242.e6
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory