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Oprm1tm1(cre)Kmel
Targeted Allele Detail
Summary
Symbol: Oprm1tm1(cre)Kmel
Name: opioid receptor, mu 1; targeted mutation 1, Konstantinos Meletis
MGI ID: MGI:7447017
Synonyms: Oprm1-2A-Cre
Gene: Oprm1  Location: Chr10:6708593-6988209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Alliance: Oprm1tm1(cre)Kmel page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:298887
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Oprm1tm1(cre)Kmel expression driven by 1 gene
 
Mutation details: A T2A-Cre sequence was inserted into the fifth exon of the Oprm1 gene and replaced a TAA stop codon by homologous recombination in C57BL/6J ES cells. (J:298887)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oprm1 (mouse)
Summary of all recombinase alleles driven by Oprm1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  54 strains or lines available
References
Original:  J:298887 Martin A, et al., A Spatiomolecular Map of the Striatum. Cell Rep. 2019 Dec 24;29(13):4320-4333.e5
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
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