Tg(Rr358-cre/ERT2)#Bpou
Transgene Detail
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Symbol: |
Tg(Rr358-cre/ERT2)#Bpou |
Name: |
transgene insertion, Blandine Poulet |
MGI ID: |
MGI:7447482 |
Synonyms: |
Acan -10 kb CreERT2 |
Transgene: |
Tg(Rr358-cre/ERT2)#Bpou Location: unknown
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Alliance: |
Tg(Rr358-cre/ERT2)#Bpou page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Rr358-cre/ERT2)#Bpou expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Acan (MGI:99602) |
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Mutation details: A chondrocyte-specific Acan enhancer A1 (Rr358), located approximately 10 kb upstream of the transcription start site of the aggrecan gene (Acan) drives Cre/ERT2 fusion protein expression in articular chondrocytes. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:291297)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Acan
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:291297 Keenan CM, et al., Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of CCN2. Dis Model Mech. 2020 Jul 2;:dmm044719 |
All: |
1 reference(s) |
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