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Tg(Rr162136-cre/ERT2)#Bpou
Transgene Detail
Summary
Symbol: Tg(Rr162136-cre/ERT2)#Bpou
Name: transgene insertion, Blandine Poulet
MGI ID: MGI:7447483
Synonyms: Acan -30 kb CreERT2
Transgene: Tg(Rr162136-cre/ERT2)#Bpou  Location: unknown  
Alliance: Tg(Rr162136-cre/ERT2)#Bpou page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Rr162136-cre/ERT2)#Bpou expression driven by 1 gene
 
Mutation detailsA chondrocyte-specific Acan enhancer (Rr162136), located approximately 30 kb upstream of the transcription start site of the aggrecan gene (Acan) drives Cre/ERT2 fusion protein expression in all chondrocytes. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:291297)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acan (mouse)
Summary of all recombinase alleles driven by Acan.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:291297 Keenan CM, et al., Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of CCN2. Dis Model Mech. 2020 Jul 2;:dmm044719
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory