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Tg(Prl-cre)#Salr
Transgene Detail
Summary
Symbol: Tg(Prl-cre)#Salr
Name: transgene insertion, Stephen A Liebhaber
MGI ID: MGI:7448387
Synonyms: Prl-Cre
Transgene: Tg(Prl-cre)#Salr  Location: unknown  
Alliance: Tg(Prl-cre)#Salr page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Prl-cre)#Salr expression driven by 1 gene
 
Mutation details: A Cre sequence was inserted into the beginning of exon 2 of the Prl ORF in a BAC clone (RP23-441I3 BAC) containing the mouse Prl locus with more than 50 kb of upstream and downstream sequences. The PRL start codon was maintained in the Cre ORF such that the protein product was the first of approximately 10 amino acids of PRL, followed by the full Cre recombinase protein. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:295321)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prl (mouse)
Summary of all recombinase alleles driven by Prl.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:295321 Peel MT, et al., The Transcription Factor NR4A2 Plays an Essential Role in Driving Prolactin Expression in Female Pituitary Lactotropes. Endocrinology. 2020 May 1;161(5)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory