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Tg(Ccr2-cre/ERT2)12Kuan
Transgene Detail
Summary
Symbol: Tg(Ccr2-cre/ERT2)12Kuan
Name: transgene insertion, Chia-Yi Kuan
MGI ID: MGI:7448543
Synonyms: CCR2-CreER(T2)
Transgene: Tg(Ccr2-cre/ERT2)12Kuan  Location: unknown  
Alliance: Tg(Ccr2-cre/ERT2)12Kuan page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Ccr2-cre/ERT2)12Kuan expression driven by 1 gene
 
Mutation details: The CreERT2 cassette was inserted into the 96-kb mouse BAC (CH25-320O8) containing the mouse Ccr2 gene. Three lines (#21, #49, and #50) from >10 founders were established. Line #21 was used for further studies. (J:314192)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ccr2 (mouse)
Summary of all recombinase alleles driven by Ccr2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:314192 Chen HR, et al., Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke. Sci Adv. 2020 Aug;6(35):eabb2119
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory