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Tg(Epo-cre)241Weng
Transgene Detail
Summary
Symbol: Tg(Epo-cre)241Weng
Name: transgene insertion 241, Roland H Wenger
MGI ID: MGI:7448900
Synonyms: Epo-CreERT2, Epo-CreERT2#241, Tg (EPO::Cre)nRhw)
Transgene: Tg(Epo-cre)241Weng  Location: unknown  Genetic Position: Chr9, Syntenic
Alliance: Tg(Epo-cre)241Weng page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Epo-cre)241Weng expression driven by 1 gene
 
Mutation details: The Cre/ERT2 cDNA sequence was targeted into the 2nd exon and 4th intron of the mouse Epo gene in the BAC clone RP24-338L14. Eight independent founder lines were generated and two of them (lines #1 and #241) were further analyzed by whole genome sequencing. Line #241 is inserted into the chr9. (J:334336)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Epo (mouse)
Summary of all recombinase alleles driven by Epo.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:334336 Imeri F, et al., Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype. Kidney Int. 2023;95:375
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory