Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp
Transgene Detail
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| Symbol: |
Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp |
| Name: |
transgene insertion 1, Luis F Parada |
| MGI ID: |
MGI:7449234 |
| Synonyms: |
CGD |
| Transgene: |
Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp Location: unknown
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| Alliance: |
Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp page
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| Transgene Type: |
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Transgenic (Epitope tag, Inducible, Inserted expressed sequence, Recombinase, Reporter) |
| Mutation: |
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Insertion
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Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
HBEGF (1839) |
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Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The 5.6 kb of the rat 5' regulatory element followed by CreERT2, histone 2B tagged enhanced GFP, and human diphtheria toxin receptor (CGD), each element separated by p2A sequences, and 668bp of the inverted second intron were used to express three proteins from one transcript in neural stem cells. Twenty-nine transgenic founder lines were identified. A single founder that displayed the specific expression pattern without detectable ectopic expression was established.
(J:299260)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Nes
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:299260 Xie XP, et al., High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31448-31458 |
| All: |
2 reference(s) |
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Analysis Tools
