Psca<em1(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7449309)

Psca^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Psca^{em1(cre/ERT2)Smoc}
Name:	prostate stem cell antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:7449309
Synonyms:	Psca^CreERT2
Gene:	Psca Location: Chr15:74586688-74588914 bp, + strand Genetic Position: Chr15, 34.26 cM
Alliance:	Psca^{em1(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Psca^{em1(cre/ERT2)Smoc} expression driven by 1 gene

The CreERT2 cassette is under the control of the Psca promoter. (J:305876)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Psca (mouse) Summary of all recombinase alleles driven by Psca. Comparative matrix view of recombinase activities Alliance mouse Psca gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Psca Mutation:	13 strains or lines available

References

Original:	J:305876 Guo W, et al., Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips. Nat Genet. 2020 Sep;52(9):908-918
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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