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Aldh1l1em1(cre/ERT2)Nju
Endonuclease-mediated Allele Detail
Summary
Symbol: Aldh1l1em1(cre/ERT2)Nju
Name: aldehyde dehydrogenase 1 family, member L1; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI ID: MGI:7450881
Synonyms: Aldh1l1-CreERT2
Gene: Aldh1l1  Location: Chr6:90527751-90576153 bp, + strand  Genetic Position: Chr6, 40.16 cM
Alliance: Aldh1l1em1(cre/ERT2)Nju page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Aldh1l1em1(cre/ERT2)Nju expression driven by 1 gene
 
Mutation details: Using a CRISPR/Cas9 system, the T2A-CreERT2 cassette was inserted into the exon containing the termination codon of the Aldh1l1. (J:330603)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aldh1l1 (mouse)
Summary of all recombinase alleles driven by Aldh1l1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1l1 Mutation:  58 strains or lines available
References
Original:  J:330603 Hu NY, et al., Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines. Neurosci Bull. 2020 May;36(5):530-544
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory