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Tbx3em1(cre/ERT2)Toyo
Endonuclease-mediated Allele Detail
Summary
Symbol: Tbx3em1(cre/ERT2)Toyo
Name: T-box 3; endonuclease-mediated mutation 1, Fumiko Toyoshima
MGI ID: MGI:7451039
Synonyms: Tbx3creERT2
Gene: Tbx3  Location: Chr5:119808734-119822789 bp, + strand  Genetic Position: Chr5, 60.34 cM
Alliance: Tbx3em1(cre/ERT2)Toyo page
Mutation
origin
Strain of Origin:  ICR
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Mutation:    Insertion
 
Tbx3em1(cre/ERT2)Toyo expression driven by 1 gene
    Using CRISPR/Cas9 technology, a 2A-CreERT2 cassette was inserted into the Tbx3 locus. (J:303437)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tbx3 (mouse)
Summary of all recombinase alleles driven by Tbx3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx3 Mutation:  49 strains or lines available
References
Original:  J:303437 Ichijo R, et al., Vasculature-driven stem cell population coordinates tissue scaling in dynamic organs. Sci Adv. 2021 Feb;7(7)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory