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Glulem2(cre/ERT2)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Glulem2(cre/ERT2)Bzsh
Name: glutamate-ammonia ligase; endonuclease-mediated mutation 2, Bin Zhou
MGI ID: MGI:7451132
Synonyms: GS-CreER
Gene: Glul  Location: Chr1:153775692-153785469 bp, + strand  Genetic Position: Chr1, 65.43 cM, cytoband G2
Alliance: Glulem2(cre/ERT2)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Glulem2(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, the CreERT2 cassette was inserted into the translational stop codon of the Glul gene, following endogenous Glul by the self-cleaving peptide 2A sequence. (J:303771)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Glul (mouse)
Summary of all recombinase alleles driven by Glul.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glul Mutation:  35 strains or lines available
References
Original:  J:303771 He L, et al., Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair. Science. 2021 Feb 26;371(6532)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory