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Tg(Tyrp1-cre/ERT2)1Jwk
Transgene Detail
Summary
Symbol: Tg(Tyrp1-cre/ERT2)1Jwk
Name: transgene insertion 1, Jin Woo Kim
MGI ID: MGI:7460347
Transgene: Tg(Tyrp1-cre/ERT2)1Jwk  Location: unknown  
Alliance: Tg(Tyrp1-cre/ERT2)1Jwk page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Tyrp1-cre/ERT2)1Jwk expression driven by 1 gene
 
Mutation details: A DNA fragment encompassing the Tyrp1 promoter region was cloned into a vector containing the cre/ERT2 sequence. The resulting 7.3 kb construct was purified for microinjection into oocytes. (J:314167)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tyrp1 (mouse)
Summary of all recombinase alleles driven by Tyrp1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:314167 Lim S, et al., mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Muller glia. Elife. 2021 Oct 22;10:e70079
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory