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Iqgap3tm2.1(cre/ERT2)Itoy
Targeted Allele Detail
Summary
Symbol: Iqgap3tm2.1(cre/ERT2)Itoy
Name: IQ motif containing GTPase activating protein 3; targeted mutation 2.1, Yoshiaki Ito
MGI ID: MGI:7461842
Synonyms: Iqgap3-2A-CreERT2
Gene: Iqgap3  Location: Chr3:87989309-88028355 bp, + strand  Genetic Position: Chr3, 38.78 cM
Alliance: Iqgap3tm2.1(cre/ERT2)Itoy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:334620
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Iqgap3tm2.1(cre/ERT2)Itoy expression driven by 1 gene
 
Mutation details: The 2A-CreERT2 sequence was inserted before the stop codon in exon 38 of the Iqgap3 gene. The neo-selection cassette was self-deleted. (J:334620)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Iqgap3 (mouse)
Summary of all recombinase alleles driven by Iqgap3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Iqgap3 Mutation:  82 strains or lines available
References
Original:  J:334620 Matsuo J, et al., Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair. Gut. 2021 Oct;70(10):1833-1846
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory