About   Help   FAQ
Krt6aem1(icre)Vk
Endonuclease-mediated Allele Detail
Summary
Symbol: Krt6aem1(icre)Vk
Name: keratin 6A; endonuclease-mediated mutation 1, Vesa Kaartinen
MGI ID: MGI:7464182
Synonyms: Krt6aiCre
Gene: Krt6a  Location: Chr15:101598363-101602746 bp, - strand  Genetic Position: Chr15, 56.97 cM
Alliance: Krt6aem1(icre)Vk page
Mutation
origin
Strain of Origin:  C57BL/6 x SJL
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Krt6aem1(icre)Vk expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing is used to introduce the iCre-pA cassettes at the Krt6a initiator methionine site in exon 1. (J:325729, J:334621)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt6a (mouse)
Summary of all recombinase alleles driven by Krt6a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt6a Mutation:  25 strains or lines available
References
Original:  J:334621 Saroya G, et al., Periderm Fate during Palatogenesis: TGF-beta and Periderm Dedifferentiation. J Dent Res. 2023 Apr;102(4):459-466
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory