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Tg(Nmur1-icre,-EGFP)1Dart
Transgene Detail
Summary
Symbol: Tg(Nmur1-icre,-EGFP)1Dart
Name: transgene insertion 1, David Artis
MGI ID: MGI:7464238
Synonyms: Nmur1iCre-eGFP, Tg(Nmur1-iCre,-eGFP)1Dart
Transgene: Tg(Nmur1-icre,-EGFP)1Dart  Location: unknown  
Alliance: Tg(Nmur1-icre,-EGFP)1Dart page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase, Reporter)
Mutation:    Insertion
 
Tg(Nmur1-icre,-EGFP)1Dart expression driven by 1 gene
 
Mutation details: The transgene was generated by replacing exons 2 and 3 of neuromedin U receptor 1 (Nmur1 gene), in the mouse BAC RP23-403I3, with a P2A-iCre-T2A-EGFP cassette followed by an FRT-flanked Kanamycin cassette. The FRT flanked kanamycin cassette was removed by FLP-mediated recombination. The modified BAC construct was microinjected into the pronucleus of C57BL/6 zygotes and randomly integrated into the mouse genome. Founder line 1 was established and then subsequently maintained (J:334817)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nmur1 (mouse)
Summary of all recombinase alleles driven by Nmur1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:334817 Tsou AM, et al., Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature. 2022 Nov;611(7937):787-793
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory