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Clec11aem3(cre/ERT2)Sjm
Endonuclease-mediated Allele Detail
Summary
Symbol: Clec11aem3(cre/ERT2)Sjm
Name: C-type lectin domain family 11, member a; endonuclease-mediated mutation 3, Sean Morrison
MGI ID: MGI:7464488
Synonyms: OlniCreER
Gene: Clec11a  Location: Chr7:43953190-43956383 bp, - strand  Genetic Position: Chr7, 28.83 cM, cytoband B3-B5
Alliance: Clec11aem3(cre/ERT2)Sjm page
Mutation
origin
Strain of Origin:  C57BL/Ka
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Clec11aem3(cre/ERT2)Sjm expression driven by 1 gene
 
Mutation details: CRISPR-Cas9 methods were used to insert iCreER sequence to replace the exons 1 and 2 of the Clec11a (Oln) gene. (J:334856)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Clec11a (mouse)
Summary of all recombinase alleles driven by Clec11a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec11a Mutation:  17 strains or lines available
References
Original:  J:334856 Shen B, et al., A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis. Nature. 2021 Mar;591(7850):438-444
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory