Cdh5<em1(cre/ERT2)Boz> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7464545)

Cdh5^{em1(cre/ERT2)Boz}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Cdh5^{em1(cre/ERT2)Boz}
Name:	cadherin 5; endonuclease-mediated mutation 1, Bo O Zhou
MGI ID:	MGI:7464545
Synonyms:	Cdh5^creER
Gene:	Cdh5 Location: Chr8:104828257-104871143 bp, + strand Genetic Position: Chr8, 53.04 cM
Alliance:	Cdh5^{em1(cre/ERT2)Boz} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Cdh5^{em1(cre/ERT2)Boz} expression driven by 1 gene

The creER sequence was inserted into and replaced the ATG site of the Cdh5 gene. (J:334866)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh5 (mouse) Summary of all recombinase alleles driven by Cdh5. Comparative matrix view of recombinase activities Alliance mouse Cdh5 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cdh5 Mutation:	59 strains or lines available

References

Original:	J:334866 Peng YJ, et al., Sertoli cells are the source of stem cell factor for spermatogenesis. Development. 2023 Mar 15;150(6):dev200706
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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