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Gad1tm3(cre/PGR*)Tama
Targeted Allele Detail
Summary
Symbol: Gad1tm3(cre/PGR*)Tama
Name: glutamate decarboxylase 1; targeted mutation 3, Nobuaki Tamamaki
MGI ID: MGI:7466336
Synonyms: GAD67-CrePR
Gene: Gad1  Location: Chr2:70392109-70432358 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Alliance: Gad1tm3(cre/PGR*)Tama page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:316938
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    mifepristone
Mutation:    Insertion
 
Gad1tm3(cre/PGR*)Tama expression driven by 1 gene
 
Mutation details: The targeting vector consists of a fusion protein of Cre recombinase plus a modified ligand binding domain of the human progesterone receptor and pgk-neo-polyA cassette followed by a Pgk-neo-p(A) cassette flanked by two Flp recognition target (frt) sites was inserted in the translational initiation site of the Gad1 gene. (J:316938)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gad1 (mouse)
Summary of all recombinase alleles driven by Gad1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:  65 strains or lines available
References
Original:  J:316938 Esumi S, et al., Characterization and Stage-Dependent Lineage Analysis of Intermediate Progenitors of Cortical GABAergic Interneurons. Front Neurosci. 2021;15:607908
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory