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Gene Expression Data
Assay Details
Assay
Reference: J:271281 Bowles J, et al., Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7466641
Gene symbol: Cyp11a1
Gene name: cytochrome P450, family 11, subfamily a, polypeptide 1
Antibody: anti-CYP11A1/SCC
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A Wt SCC: embryonic day 13.5 (more )
Note: Double labeled: green - Cyp11a1; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS21: Leydig cell Leydig cell Present 4A XY Wt left , 4A XY Wt left inset
Specimen 4A KO SCC: embryonic day 13.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Double labeled: green - Cyp11a1; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS21: Leydig cell Leydig cell Present 4A XY KO left inset , 4A XY KO left The number of expressing cells is decreased in the mutant relative to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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