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Igs51tm1(CAG-flpe,-EGFP)Itoi
Targeted Allele Detail
Summary
Symbol: Igs51tm1(CAG-flpe,-EGFP)Itoi
Name: intergenic site 51; targeted mutation 1, Keiichi Itoi
MGI ID: MGI:7466667
Synonyms: Actb-FLPe, FLP deleter
Gene: Igs51  Location: unknown  Genetic Position: Chr5, Syntenic
Alliance: Igs51tm1(CAG-flpe,-EGFP)Itoi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:279641
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Epitope tag, Recombinase, Reporter)
Mutation:    Insertion
 
Igs51tm1(CAG-flpe,-EGFP)Itoi expression driven by 1 gene
 
Mutation detailsThe following elements were inserted downstream of the Actb gene in intergenic region Igs51 via homologous recombination: CAG promoter, the flpe recombinase gene, IRES sequences, N-terminal FLAG tagged EGFP reporter gene, SV40 poly(A) signal sequences, a loxP site, a neomycin resistance gene cassette, and a second loxP site. (J:279641)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs51 Mutation:  0 strains or lines available
References
Original:  J:279641 Kono J, et al., Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse. Brain Struct Funct. 2017 May;222(4):1705-1732
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory