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Tacr1tm1.1(cre/GFP)Xzd
Targeted Allele Detail
Summary
Symbol: Tacr1tm1.1(cre/GFP)Xzd
Name: tachykinin receptor 1; targeted mutation 1, Xinzhong Dong
MGI ID: MGI:7468609
Synonyms: NK1R-GFP-Cre
Gene: Tacr1  Location: Chr6:82379315-82537085 bp, + strand  Genetic Position: Chr6, 35.94 cM, cytoband D1
Alliance: Tacr1tm1.1(cre/GFP)Xzd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:319932
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Tacr1tm1.1(cre/GFP)Xzd expression driven by 1 gene
 
Mutation details: The allele was generated by using a homologous recombination knock-in approach. The GFP-Cre transgene was integrated into the start codon of the Tacr1 gene using two homologous arms targeting the sequences. Cre and GFP fusion protein is expressed under Tacr1 (NK1R) promotor control. (J:319932)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tacr1 (mouse)
Summary of all recombinase alleles driven by Tacr1.
 

Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tacr1 Mutation:  40 strains or lines available
References
Original:  J:319932 Xu Q, et al., Astrocytes contribute to pain gating in the spinal cord. Sci Adv. 2021 Nov 5;7(45):eabi6287
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory