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Mafaem1(cre)Xzd
Endonuclease-mediated Allele Detail
Summary
Symbol: Mafaem1(cre)Xzd
Name: MAF bZIP transcription factor A; endonuclease-mediated mutation 1, Xinzhong Dong
MGI ID: MGI:7468617
Synonyms: MafA-Cre
Gene: Mafa  Location: Chr15:75617339-75620077 bp, - strand  Genetic Position: Chr15, 34.82 cM
Alliance: Mafaem1(cre)Xzd page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout, Recombinase)
Mutation:    Insertion
 
Mafaem1(cre)Xzd expression driven by 1 gene
    Using a CRISPR-Cas9 approach, the entire Mafa coding sequence was replaced with Cre transgene. (J:319932)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mafa (mouse)
Summary of all recombinase alleles driven by Mafa.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafa Mutation:  20 strains or lines available
References
Original:  J:319932 Xu Q, et al., Astrocytes contribute to pain gating in the spinal cord. Sci Adv. 2021 Nov 5;7(45):eabi6287
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory