Ror2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:156970 Mikels A, et al., Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7481219
Gene symbol:	Ror2
Gene name:	receptor tyrosine kinase-like orphan receptor 2

Antibody:	anti-Ror2 (rabbit)
Detection system:	Secondary antibody

Results

4C WT Ror2 ©

Specimen 4C WT: embryonic day 14.5; Ror2^tm1Ymi/Ror2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Present	Regionally restricted	4C WT Ror2	Expression is in a subset of cells that stain positive for alpha-smooth muscle actin.

4C KO Ror2 ©

Specimen 4C KO: embryonic day 14.5; Ror2^tm1Ymi/Ror2^tm1Ymi (more

)

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Absent		4C KO Ror2

Specimen 5A Ror2^+/-: embryonic day 16.5; Ror2^tm1Ymi/Ror2⁺ (more

)
Note: Double labeled: red - Ror2; green - Shh (assay MGI:7481221).

Structure	Level	Pattern	Image	Note
TS24: lung mesenchyme	Present		5A Ror2/Shh 20X Ror2^+/- , 5A Ror2/Shh 10X Ror2^+/- , 5A Ror2/Shh 40X Ror2^+/-

Specimen 5A Ror2^-/-: embryonic day 16.5; Ror2^tm1Ymi/Ror2^tm1Ymi (more

)
Note: Double labeled: red - Ror2; green - Shh (assay MGI:7481221).

Structure	Level	Pattern	Image	Note
TS24: lung mesenchyme	Absent		5A Ror2/Shh 20X Ror2^-/- , 5A Ror2/Shh 40X Ror2^-/- , 5A Ror2/Shh 10X Ror2^-/-

5B anti-Ror2 ©

Specimen 5B: embryonic day 16.5; Ror2^tm1Ymi/Ror2⁺, Axin2^tm1Wbm/Axin2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: lung mesenchyme	Present		5B anti-Ror2

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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