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Taar6tm1.1(cre)Qli
Targeted Allele Detail
Summary
Symbol: Taar6tm1.1(cre)Qli
Name: trace amine-associated receptor 6; targeted mutation 1.1, Qian Li
MGI ID: MGI:7482326
Synonyms: Taar6-ires-Cre
Gene: Taar6  Location: Chr10:23860507-23861544 bp, - strand  Genetic Position: Chr10, 11.4 cM
Alliance: Taar6tm1.1(cre)Qli page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:322210
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Taar6tm1.1(cre)Qli expression driven by 1 gene
 
Mutation detailsA sequence encoding Cre was introduced into the 3 untranslated sequence in the Taar6 gene immediately following the stop codon with an IRES sequence preceding the Cre sequence to allow bicistronic expression of TAAR6 and Cre. The targeting construct included a cassette of the neomycin gene flanked by FRT sites. The neomycin gene was removed by crossing the mice to a germline Flp recombinase line. (J:322210)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Taar6 (mouse)
Summary of all recombinase alleles driven by Taar6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taar6 Mutation:  23 strains or lines available
References
Original:  J:322210 Fei A, et al., Coordination of two enhancers drives expression of olfactory trace amine-associated receptors. Nat Commun. 2021 Jun 18;12(1):3798
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory