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Tg(Fgf1-RFP,-cre/ERT2)13AChiu
Transgene Detail
Summary
Symbol: Tg(Fgf1-RFP,-cre/ERT2)13AChiu
Name: transgene insertion 13A, Ing-Ming Chiu
MGI ID: MGI:7482681
Synonyms: F1A-CreERT2
Transgene: Tg(Fgf1-RFP,-cre/ERT2)13AChiu  Location: unknown  
Alliance: Tg(Fgf1-RFP,-cre/ERT2)13AChiu page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Mutation:    Insertion
 
Tg(Fgf1-RFP,-cre/ERT2)13AChiu expression driven by 1 gene
 
Mutation details: The 131.5 kb transgene consists of an RFP-IRES-CreERT2polyA expression cassette inserted into a mouse bacterial artificial chromosome (BAC) clone RP23-193N23 including Fgf1 5' UTR (127.7 kb), exon 1A, and 1B sequence containing the promoter for alternatively spliced to the first protein-coding exon 1A isoform predominantly expressed in the heart. Three founders 13A, 22A, and 25A were confirmed. Line #13A with the highest expression of Cre recombinase in the heart was chosen for all the following studies. (J:323281)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fgf1 (mouse)
Summary of all recombinase alleles driven by Fgf1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:323281 Hsu YC, et al., Establishing F1A-CreER(T2) Mice to Trace Fgf1 Expression in Adult Mouse Cardiomyocytes. Cells. 2021 Dec 30;11(1)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory