Nphs1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:198192 Huang J, et al., The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn. 2013 Jun;242(6):790-9
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7486053
Gene symbol:	Nphs1
Gene name:	nephrosis 1, nephrin

Antibody:	nephrin Antibody (N-20): sc-19000
Detection system:	Secondary antibody coupled to fluorescein

Results

6M ©

Specimen 6M: embryonic day 17.5 (more

)
Note: Wildtype littermates were used, but specific genetic background was not mentioned.

Structure	Cell Type	Level	Pattern	Image	Note
TS25: visceral epithelium of maturing renal corpuscle	podocyte	Present		6M

6N ©

Specimen 6N: embryonic day 17.5; Sox4^tm1Vlf/Sox4^tm1Cle, Tg(Six2-EGFP/cre)1Amc/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS25: visceral epithelium of maturing renal corpuscle	podocyte	Present		6N	Similar as in the wild-type control.

6O ©

Specimen 6O: postnatal day 7 (more

)
Note: Wildtype littermates were used, but specific genetic background was not mentioned.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: visceral epithelium of mature renal corpuscle	podocyte	Present		6O

6P ©

Specimen 6P: postnatal day 7; Sox4^tm1Vlf/Sox4^tm1Cle, Tg(Six2-EGFP/cre)1Amc/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: visceral epithelium of mature renal corpuscle	podocyte	Weak		6P	Markedly reduced expression compared with the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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